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名称 Principles of gene manipulation and genomics
索引号 Q78/E20071.7
分类号 Q78
Q78(基因工程(遗传工程))
Q7(分子生物学)
Q(生物科学)
作者 Primrose、 S. B.、Twyman、 Richard M.、Primrose、 S. B. Principles of gene manipulation.、Primrose、 S. B. Principles of genome analysis and genomics.、
出版社 Malden, MA ; Oxford : Blackwell Publishing, c2006.
ISBN
页数 xxii, 644 p. : ill. ; 28 cm.
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注解 Rev. ed. of: Principles of gene manipulation. 6th ed. 2001 and Principles of genome analysis and genomics / Sandy B. Primrose, Richard M. Twyman. 3rd ed. 2003. 附註 Includes bibliographical references (p. [547]-626) and index. 內容 Gene manipulation in the post-genomics era -- Basic techniques -- Cutting and joining DNA molecules -- Basic biology of plasmid and phage vectors -- Cosmids, phasmids, and other advanced vectors -- Gene cloning strategies -- Sequencing genes and short stretches of DNA -- Changing genes : site-directed mutagenesis and protein engineering -- Bioinformatics -- Cloning in bacteria other than Escherichia coli -- Cloning in Saccharomyces cerevisiaea and other fungi -- Gene transfer to animal cells -- Genetic manipulation of animals -- Gene transfer to plants -- Advanced transgenic technology -- The organization and structure of genomes -- Mapping and sequencing genomes -- Comparative genomics -- Large-scale mutagenesis and interference -- Analysis of the transcriptome -- Proteomics I : expression analysis and characterization of proteins -- Proteomics II : analysis of protein structures -- Proteomics III : protein interactions -- Metabolomics and global biochemical networks -- Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci -- Applications of recombinant DNA technology.