大拱桥--暨南大学学生门户 » 图书馆 » 抗肿瘤,抗癌药物 » Novel anticancer agents : strategies for discovery and clinical testing = 抗癌新药 : 发现与临床试验策略
名称 Novel anticancer agents : strategies for discovery and clinical testing = 抗癌新药 : 发现与临床试验策略
索引号 R979.1/E20061-2
分类号 R979.1
R979.1(抗肿瘤,抗癌药物)
R97(药品)
R9(药学)
R(医药,卫生)
作者
出版社 北京 : 科学出版社, c2007.
ISBN
页数 9, v-xv, 437 p., [20] p. of plates : ill. (some col.) ; 26 cm.
价格
标签
简介
注解 Reprint. Originally published: Oxford : Academic Press, c2006. 0120885611 (hbk.) 內容 A survey of novel molecular targets for anticancer drug discovery -- Microarrays: small spots produce major advances in pharmacogenomics -- Strategies to target chemotherapeutics to tumors -- QSAR and pharmacophore mapping strategies in novel anticancer drug discovery -- Applications of nuclear magnetic resonance and mass spectrometry to anticancer drug discovery -- Antisense strategies for the development of novel cancer therapeutics -- Antibodies and vaccines as novel cancer therapeutics -- Inhibitors as targets for cancer therapy -- Preclinical testing and validation of novel anticancer agents -- Surrogate end points and biomarkers for early trials of novel anticancer agents -- Regulatory considerations in clinical trials of novel anticancer drugs -- Improving the efficacy and safety of anticancer agents: the role of pharmacogenetics -- Imaging of pharmacodynamic end points in clinical trials -- Devising proof-of-concept strategies in oncology clinical trials -- Clinical trial designs for cytostatic agents and agents directed at novel molecular targets -- Cancer gene therapy clinical trials: from the bench to the clinic -- Molecular targets for radiosensitization -- Patient accrual to clinical trials.